Case of a Sister Mary Joseph’s Nodule in Pancreatic Adenocarcinoma: a Diagnostic challenge

Background: Sister Mary Joseph Nodule (SMJN) is a rare metastatic umbilical nodule with primary tumor genital or gastrointestinal sites. Pancreas location for metastases. Pancreatic adenocarcinoma associated SMJN usually arise from the body and tail of pancreas. We report case SMJ nodule’s as cutaneous manifestation pancreatic head cancer. Case Report: A 59-year-old man, presented epigastric, back pain weight loss. On examination, an was noted. Investigations confirmed sister cancer metastasis. Discussion Conclusion: remains origin most commonly digestive. Due poor prognosis, early detection systematic biopsy any mass indispensable.